가토에서 흡수성 차폐막 Biomech^®의 골재생 효과
The Effect of Absorbable Membrane (BioMesh^®) on Bone Regeneration in Rabbit
구강과학- 전남대학교 2001년 13권 3호 p.258 ~ 267
김태훈, 유선열,
소속 상세정보
김태훈 ( ) - 전남대학교 치과대학 구강악안면외과학교실
유선열 ( ) - 전남대학교 치의학연구소
KMID : 0988420010130030258
Abstract
The purpose of the present study was to investigate the effect of absorbable membrane (BioMesh^®) on bone regeneration in the rabbit by evaluating biodegradability, biocompatibility and bone regenerative capacity. Eight rabbits, weighing about 2kg, were used. Two bone defects, 8 mm in diameter and 7 mm in depth, were made. In the experimental group, the bone defect was covered with BioMesh^® absorbable membrane. In the control group, induced spontaneous healing. The rabbits were sacrificed at 2, 4, 6, and 8 weeks after the operation. Radiographic and microscopic examination were performed. Results obtained were as follows:
After 2 weeks, proliferation of the fibrous tissue was observed in the control group, but the newly formed cartilage and more active bone formation were noted in the experimental group. After 4 weeks, the new bone formation appeared in the control group, and in the experimental group, the bone trabeculi were densely aligned and matured. After 6 weeks, complete resorption of the BioMesh^® membrane occurred in the experimental group. Both experimental and control group acquired dense osseous coverage, after 8 weeks.
These results suggest that the BioMesh^® absorbable membrane contributes new bone formation by guiding bone regeneration in the early stage.
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